Small airway function in obese individuals with self-reported asthma

Small airway inflammation in asthma

Asthma was originally described as an inflammatory disease that predominantly involves the central airways. Pathological and physiological evidence reported during the past few years suggests that the inflammatory process extends beyond the central airways to the peripheral airways and the lung parenchyma. The small airways are capable of producing T-helper-2 cytokines, as well as chemokines, a...

Airway and systemic inflammation in obese children with asthma.

Obese asthma presents via altered airway and systemic inflammation in adults. This has not been comprehensively described in children. The aim of the present study was to compare airway and systemic inflammation in obese and nonobese asthmatic children and controls. In a cross-sectional study, children aged 8-17 years were assigned to one of four groups: obese asthma (OA, n=74); nonobese asthma...

Airway and Systemic Inflammation in Obese Children With Asthma

METHODS. This retrospective review included subjects from 2 cross-sectional studies conducted to assess the relationship between pediatric asthma and adiposity. Selected patients underwent somatometric measurements and skinfold thickness–mediated body fat assessment at 4 sites. The International Obesity Task Force cutoff points were used to categorize patients as normal weight, overweight, or o...

Predictors of self-reported psychosocial outcomes in individuals with dementia.

PURPOSE Little is known about the illness experience from the perspective of individuals with dementia (IWDs), as most quantitative research has focused on IWDs' psychosocial issues from proxy reports. The primary aim of this study was to better understand the impact of the illness experience on well-being from the perspective of the IWD through the framework of the Stress Process Model for Ind...

Self-reported Fatigue in Individuals with Knee Osteoarthritis